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Ribavirin
An antiviral agent
Product Overview
Product Name: Ribavirin
Alternate Name/Synonyms: 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
Description: Ribavirin is a nucleoside analog that inhibits the replication of both DNA and RNA viruses, including influenza type A and type B. Ribavirin, as ribavirin 5’-phosphate, affects virus-infected cells primarily by inhibiting the enzyme inosine 5’-monophosphate (IMP) dehydrogenase. It potently suppresses eIF4E-mediated oncogenic transformation of murine cells in vitro, of tumor growth of a mouse model of eIF4E-dependent human squamous cell carcinoma in vivo, and of colony formation of eIF4E-dependent acute myelogenous leukemia cells derived from human patients.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 36791-04-5
Molecular Formula: C₈H₁₂N₄O₅
Molecular Weight: 244.2
Purity: ≥98% by HPLC
Solubility:H2O (100 mM) or DMSO (100 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
InChi: InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
InChi Key: IWUCXVSUMQZMFG-AFCXAGJDSA-N
PubChem CID: 37542
MDL Number: MFCD00058564
USAGE: For Research Use Only! Not For Use in Humans. |