IGF-II, HUMAN RECOMBINANT, MG

IGF-II, insulin-like growth factors II
Description:
IGF-II
Trade Name:
Upstate (Millipore)
Qty/Pk:
25 µg
Key Applications:
Cell Culture
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Entrez Gene Summary:
This gene encodes a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is an imprinted gene and is expressed only from the paternally inherited allele. It is a candidate gene for eating disorders. There is a read-through, INS-IGF2, which aligns to this gene at the 3' region and to the upstream INS gene at the 5' region. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
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UniProt Summary:
FUNCTION: SwissProt: P01344 # The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.
SIZE: 180 amino acids; 20140 Da
SUBCELLULAR LOCATION: Secreted.
SIMILARITY: SwissProt: P01344 ## Belongs to the insulin family.
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Species:
Human
Brand Family:
Upstate
Source:
Recombinant DNA expressed in E. coli.
Presentation:
lypholized from 0.1M acetic acid solution
Gene Symbol:
IGF2
FLJ22066
FLJ44734
pp9974
IGF-II
ORFNames=PP1446
INSIGF
C11orf43
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Product Name:
IGF-II
Quality Assurance:
Routinely evaluated in an ATP endpoint assay
Physical Form:
Lyophilized
UniProt Number:
P01344
Entrez Gene Number:
NM_000612.3
NM_001007139.3
Purification Method:
Sterilized through a 0.2 micron membrane filter