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HMTase Inhibitor III, BIX-01338
1-(4-(4-methoxybenzoyloxy)phenethyl)-2-(4-(trifluoromethyl)benzamido)-1H-benzo[d]imidazole-5-carboxylic acid, Hydrate, 1-(2-(4-(4-Methoxybenzoyloxy)phenyl)ethyl)-2-(4-trifluoromethylbenzoylamino)-1H-benzoimidazole-5-carboxylic acid, Hydrate, EHMT1/GLP Inhibitor I, EHMT2/G9a Inhibitor III
A cell-permable amino-benzimidazolo compound that inhibits a broad-spectrum of histone methyltransferases, including PRMT1, SET7/9, G9a, SUV39H1, and GLP (effective conc. = 15 µM) in a SAM-competitive manner. BIX-01338 is reported to affect the growth of mES, MEF, and HeLa cells at concentrations needed for HMT inhibition, limiting its use in HMTase studies to cell-free systems only.
产品信息
Form Off-white powder
Molar mass 621.6
Protect from Light 是的
Hygrocopic 是的
Packaged under inert gas 是的
Purity ≥97% by HPLC
Solubility DMSO
Chemical formula C32H24F3N3O6 • H2O
商店和运输信息
Storage -20°C
Ship Dry Ice Only
Standard Handling |