InSolution? MG-132 in EtOH, ≥95% by HPLC

InSolution™ MG-132 in EtOH, ≥95% by HPLC
Proteasome Inhibitor XI
Potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM). Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. Activates c-Jun N-terminal kinase (JNK1) which initiates apoptosis. Inhibits NF-κB activation (IC50 = 3 µM). This material is ≥95% pure by HPLC. A material with ≥98% purity by HPLC (Cat. No. 474791) and the solid form of this compound (Cat. No. 474787) are also available.
产品信息
Peptide Sequence  Z-Leu-Leu-Leu-CHO
Form  Liquid
Formulation  A 20 mM (10 mg/1.05 ml) solution of MG-132, ≥95% by HPLC (Cat. No. 474787) in EtOH.
Primary Target Ki  Ki = 4 nM for proteasomal inhibition
Secondary target  IKK
Molar mass  475.6
Protect from Light  是的
Avoid freeze/thaw  是的
Packaged under inert gas  是的
Cell permeable  是的
Reversible  是的
Purity  ≥95% by HPLC
Chemical formula  C26H41N3O5
商店和运输信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage  ≤ -70°C
Ship  Dry Ice Only
Flammable