Ceranib-2 Ceranib 2, Ceranib2, 3-(3-(4-methoxyphenyl)acryloyl)-4-phenylquinolin-2(1H)-one A cell-permeable, potent inhibitor of ceramidase (IC50 = 28 µM) with anti-proliferative and proapoptotic properties. Shown to block the proliferation of SKVO3, ovarian adenocarcinma cells (IC50 = 730 nM) in the G2/M phase. When used in combination with paclitaxel, it increases tumor chemosentitvity and exhibits additive chemotherapeutic effects. Reduces tumor burden in Balb/c mice when administered intraperitoneally (20-50 mg/kg) without affecting the total body weight. 产品信息 Form White powder Molar mass 381.42 Protect from Light 是的 Packaged under inert gas 是的 Purity ≥98% by HPLC Solubility DMSO Chemical formula C25H19NO3 商店和运输信息 Storage -20°C Ship Shipped at Ambient Temperature or with Blue Ice or with Dry Ice Standard Handling
