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Loxoribine
A selective TLR7 ligand
Product Overview
Product Name: Loxoribine
Alternate Name/Synonyms: 7-Allyl-8-oxoguanosine ; RWJ21757
Description: A guanosine derivative that acts as a selective ligand for Toll-like receptor 7 (TLR7) via IFN. Activates natural killer cells and primes cytolytic precursor cells for activation by IL-2.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 121288-39-9
Molecular Formula: C₁₃H₁₇N₅O₆
Molecular Weight: 339.3
Purity: ≥97% by HPLC
Solubility:DMSO (30 mg/ml) or water (10 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and moisture
SMILES: C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O
InChi: InChI=1S/C13H17N5O6/c1-2-3-17-6-9(15-12(14)16-10(6)22)18(13(17)23)11-8(21)7(20)5(4-19)24-11/h2,5,7-8,11,19-21H,1,3-4H2,(H3,14,15,16,22)/t5-,7-,8-,11-/m1/s1
InChi Key: VDCRFBBZFHHYGT-IOSLPCCCSA-N
PubChem CID: 60737
MDL Number: MFCD00867591
USAGE: For Research Use Only! Not For Use in Humans. |