IQ-1 Bulk Request IQ-1 in conjunction with Wnt3a has been shown to be sufficient to maintain murine embryonic stem cell proliferation in the absence of serum. Binds to the PR72/PR130 subunit of protein phosphatase PP2A preventing β-catenin from switching co-activator usage from CBP to p300 leading to an increase in β-catenin/CBP-driven transcription at the expense of β-catenin/p300-driven transcription. Upregulates expression of Oct4 and Sox2 transcription factors. Product Specification Alternative Name: 2-(4-Acetylphenylazo)-2-(3,3-dimethyl-3,4-dihydro-2H-isoquinolin-1-ylidene)-acetamide Formula: C21H22N4O2 MW: 362.4 CAS: 331001-62-8 Purity: ≥98% (TLC) Appearance: Orange solid. Solubility: Soluble in DMSO (25mg/ml) or in 100% ethanol (10mg/ml). Long Term Storage: -20°C Use/Stability: Stable for at least 6 months after receipt when stored at -20°C. Solutions can be stored at -20°C for up to 3 months.
