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Screen Quest� Colorimetric Chloride Channel Assay Kit
Cat # 36350
Storage F/D/L (see storage codes below)
Unit Size 10 Plates
Ex (nm) 630
Chloride channels have a variety of important physiological and cellular functions that include regulation of pH, volume homeostasis, organic solute transport, cell migration, cell proliferation and differentiation. Chloride channels represent valuable drug targets. A number of chronic disease states such as cystic fibrosis and Bartter's syndrome are due to defects in chloride channel functions. However, the existing technologies for screening chloride channel modulators are a compromise between throughput, sensitivity and physiological relevance. Screen Quest� Colorimetric Chloride Channel Assay Kit provides a sensitive and robust colorimetric method for studying chloride channels. The assay is based on our proprietary iodide indicator (Iodide Blue�) for measuring iodide concentration, as low as 30 nM of iodide was detected by this assay. Screen Quest� Chloride Channel Assay Kit provides an optimized assay method for monitoring chloride channels. The assay can be performed in a convenient 96-well or 384-well microtiter-plate format and easily adapted to automation.
Detailed Information: Protocol References MSDS
Related Products: Chloride Channels pH and Ion Indicators
Storage Codes:
D = Desiccated
L = Avoid light
F = Freeze (<-15 癈)
R = Refrigerated (2-4 癈)
RT = Room temperature (4-50 癈)
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