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Resorufin alpha-D-galactopyranoside
Cat # 14021
Storage F/D/L (see storage codes below)
Unit Size 5 mg
Ex (nm) 571
Em (nm) 585
MW 375.33
Solvent DMSO
Resorufin alpha-D-galactopyranoside is a sensitive fluorogenic substrate that generates a red fluorescent product (resorufin) upon interaction with alpha-galactosidase. It is used for measuring alpha-galactosidase activitites and high throughput screening of alpha-galactosidase inhibitors. Alpha-galactosidase is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry's disease, a rare lysosomal storage disorder and sphingolipidosis that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
Detailed Information: Protocol References MSDS Spectrum
Related Products: Hydrolytic Enzymes Reporter Gene Enzymes
Storage Codes:
D = Desiccated
L = Avoid light
F = Freeze (<-15 癈)
R = Refrigerated (2-4 癈)
RT = Room temperature (4-50 癈) |