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Gossypol-acetic acid
Description
A potential male anti-fertility agent from cotton that exhibits a wide spectrum of toxicity. It was found to have cytotoxic effects on human cancer cell lines. It is a potent telomerase inhibitor.
Specifications
Cas No. 12542-36-8
Product ID G5875
Product Name Gossypol-acetic acid
Chemical Name 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1- methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde-acetic acid
Synonym 2,2'-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene)-acetic acid
Formula Wt. 578.61
Melting Point 184
Purity ≥98%
Solubility Soluble in DMSO, methanol or ethanol. Insoluble in water.
Store Temp -20oC
References Nadakavukaren MJ, Sorensen RH, Tone JN. Cell Tissue Res. 204:293-6 (1979). Sakesena SK, Salmonsen R, Lau IF, Chang MC. Contraception. 24:203-14 (1981). Tuszynski GP, Cossu G. Cancer Res. 44:768-71 (1984). Mego M. Bratisl Lek Listy. 103:378-81 (2002).
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