|
Glucaric acid, calcium salt
Description
A nontoxic, natural compound. One of its derivatives 1,4-GL increases detoxification of carcinogens and tumor promoters/ progressors by inhibiting beta-glucuronidase and preventing hydrolysis of their glucuronides. When it was fed during the initiation, promotion, or both phases of chemically induced rat mammary carcinogenesis it was found to reduce tumor incidence and multiplicity.
Specifications
Cas No. 5793-89-5
Product ID G4518
Product Name Glucaric acid, calcium salt
Synonym D-Glucaric acid, calcium salt; D-Saccharic acid, calcium salt; Calcium D-glucarate
Formula Wt. 320.3
Melting Point >250oC
Purity ≥98%
Solubility Soluble in water.
Store Temp Ambient
References Walaszek Z, Szemraj J, Narog M, Adams AK, Kilgore J, Sherman U, Hanausek M, Cancer Detect. Prev. 21:178-190 (1997). Abou-Issa H, Moeschberger M, el-Masry W, Tejwani S, Curley RW jr, Webb TE. Anticancer Res. 15:805-810 (1995).
|