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Fasudil Hydrochloride
Description
is a potent Rho-kinase inhibitor and vasodilator. Since it was discovered, it has been used for the treatment of cerebral vasospasm, which is often due to subarachnoid hemorrhage, as well as to improve the cognitive decline seen in stroke victims. It has been found to be effective for the treatment of pulmonary hypertension. It was demonstrated in February of 2009 that Fasudil could also be used to enhance memory and improve the prognosis of Alzheimers patients.
Specifications
Cas No. 105628-07-7
Product ID F0275
Product Name Fasudil Hydrochloride
Formula Wt. 327.83
Store Temp Ambient
"[Treatment of cerebral vasospasm by a protein kinase inhibitor AT 877]" (in Japanese). No to Shinkei 45 (9): 819–24. PMID 8217408. Doggrell SA (2005). "Rho-kinase inhibitors show promise in pulmonary hypertension.". Expert Opin Investig Drugs 14 (9): 1157–1159. doi:10.1517/13543784.14.9.1157. PMID 16144499. Huentelman, Matthew J.; Stephan, DA; Talboom, J; Corneveaux, JJ; Reiman, DM; Gerber, JD; Barnes, CA; Alexander, GE et al. (2009). "Peripheral delivery of a ROCK inhibitor improves learning and working memory". Behavioral Neuroscience 123 (1): 218. doi:10.1037/a0014260. PMID 19170447
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