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Etodolac
Description
A COX-2 inhibitor with anti-inflammatory and analgesic activity. It has been shown to inhibit growth and PCNA expression and induce cell cycle arrest in human hepatocellular carcinoma cell lines, in addition to suppressing the occurrence of aberrant crypt foci and tumors in colitis-induced tumorigenesis in rats.
See more information about other Cox 2 Inhibitors
Specifications
Cas No. 41340-25-4
Product ID E7556
Product Name Etodolac
Chemical Name Pyrano(3,4-b)indole-1-acetic acid, 1,8-diethyl-1,3,4,9- tetrahydro-
Synonym Etodolic acid; Etogesic; Lodine; Tedolan; Ultradol.
Formula Wt. 287.35
Melting Point 145oC-148oC
Purity ≥98%
Solubility Soluble in alcohols, chloroform, DMSO or aqueous polyethylene glycol.
Store Temp +4oC
References Cheng J, Imanishi H, Liu W et al. Cancer Sci. 95:666-73 (2004). Takeda J, Kitajima K, Fujii S et al. Oncol Rep. 11:981-5 (2004). Lynch S, Brogden RN. Drugs. 31:288-300 (1986).
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