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Estrone
Description
Estradiol metabolite found to reduce colon tumorigenesis in mice, independently of ERalpha. Found to inhibit BCRP-mediated drug efflux and overcome drug resistance.
Specifications
Cas No. 53-16-7
Product ID E7378
Product Name Estrone
Chemical Name 3-Hydroxyestra-1,3,5(10)-tri-en-17-onne
Synonym Oestrone; Flliculinn; Tokokin; Hiestrone; Glandubolin; Kolponn; Homrovarine; Wynestron; Kestron; Follestrine
Formula Wt. 270.37
Melting Point 254.5
Purity ≥97%
Solubility Soluble in water, alcohol, acetone, chloroform, benzene, dioxane, pyridine or fixed alkali hydroxide solutions.
Store Temp Ambient
References Guo JY et al.J Nutr.134:179-82(2004). Imai Y, Tsukahara S, Ishikawa E, Tsuruo T, Sugimoto Y.Jpn J Cancer Res.93:231-5(2002).
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