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Daptomycin
Description
A novel lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms. It is a naturally-occurring compound found in the soil saprotroph Streptomyces roseosporus. Daptomycin has been shown to be not inferior to standard therapies (nafcillin, oxacillin, flucloxacillin or vancomycin) in the treatment of bacteraemia and right-sided endocarditis caused by Staphylococcus aureus.
Specifications
Cas No. 103060-53-3
Product ID D0363
Product Name Daptomycin
Chemical Name N-decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo -3-methyl-L-glutamyl-3-anthraniloyl-L-alanine[egr]1-lactone
Formula C72H101N17O26
Formula Wt. 1619.70
References Fowler VG, Boucher HW, Corey GR (Aug 2006). "Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus". N Engl J Med 355 (7): 653–65. doi:10.1056/NEJMoa053783
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