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APF
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产品编号: |
10157-500
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产品名称:
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APF .0 订购此产品 |
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供应商:
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Cayman |
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规格: |
500 碌g |
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目录价: |
1909.6 |
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库存状态: |
3周 |
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CAS编号:
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359010-70-1 |
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应用范围: |
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种属来源: |
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相关信息: |
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APF
Cayman Chemical Item Number 10157
Description
The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including, neurodegeneration and aging, cancer, and infectious diseases.1↗ There are a number of fluorescent reagents that can be used to detect free radicals, such as 2,7-dichlorodihydrofluorescein (DCDHF), but they have significant limitations due to their facile oxidation by light and numerous non-radical oxidants such as hydrogen peroxide (H2O2).2↗ APF is an aromatic amino-fluorescein derivative that has little intrinsic fluorescence. It undergoes oxidation only by the hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, but is inert to NO, H2O2, superoxide, and other oxidants. Upon oxidation, APF is converted to the highly fluorescent molecule fluorescein, allowing the simple direct detection of highly reactive biological radicals.3↗
Formal Name 2-[6-(4-aminophenoxy)-3-oxo-3H-xanthen-9-yl]-benzoic acid
CAS Number 359010-70-1
Molecular Formula C26H17NO5
Formula Weight 423.4
Formulation A solution in methyl acetate
Purity >98%
λmax 223, 278 nm
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES Nc1ccc(cc1)Oc1ccc2c(c1)Oc1cc(O)ccc1C12OC(=O)c2ccccc12
InCHI Code 1S/C26H17NO5/c27-15-5-8-17(9-6-15)30-18-10-12-22-24(14-18)31-23-13-16(28)7-11-21(23)26(22)20-4-2-1-3-19(20)25(29)32-26/h1-14,28H,27H2
InCHI Key SKRNNOWWEXPZBB-UHFFFAOYSA-N |
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保存条件: |
-20°C |
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说明书地址: |
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