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APF

产品编号: 10157-500     查看说明书
产品名称: APF  .0   订购此产品 
供应商: Cayman
规格: 500 碌g
目录价: 1909.6
库存状态: 3周
CAS编号: 359010-70-1
应用范围:
种属来源:
相关信息:
APF Cayman Chemical Item Number 10157 Description The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including, neurodegeneration and aging, cancer, and infectious diseases.1↗ There are a number of fluorescent reagents that can be used to detect free radicals, such as 2,7-dichlorodihydrofluorescein (DCDHF), but they have significant limitations due to their facile oxidation by light and numerous non-radical oxidants such as hydrogen peroxide (H2O2).2↗ APF is an aromatic amino-fluorescein derivative that has little intrinsic fluorescence. It undergoes oxidation only by the hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, but is inert to NO, H2O2, superoxide, and other oxidants. Upon oxidation, APF is converted to the highly fluorescent molecule fluorescein, allowing the simple direct detection of highly reactive biological radicals.3↗ Formal Name 2-​[6-​(4-​aminophenoxy)-​3-​oxo-​3H-​xanthen-​9-​yl]-​benzoic acid CAS Number 359010-70-1 Molecular Formula C26H17NO5 Formula Weight 423.4 Formulation A solution in methyl acetate Purity >98% λmax 223, 278 nm Stability 1 year Storage -20°C Shipping Room temperature in continental US; may vary elsewhere SMILES Nc1ccc(cc1)​Oc1ccc2c(c1)​Oc1cc(O)​ccc1C12OC(=O)​c2ccccc12 InCHI Code ​1S/C26H17NO5/c27-15-5-8-17(9-6-15)​30-18-10-12-22-24(14-18)​31-23-13-16(28)​7-11-21(23)​26(22)​20-4-2-1-3-19(20)​25(29)​32-26/h1-14,28H,27H2 InCHI Key SKRNNOWWEXPZBB-UHFFFAOYSA-N
保存条件: -20°C
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