CAY10649

产品编号：	10804-1 查看说明书
产品名称：	CAY10649 .0 订购此产品
供应商：	Cayman
规格：	1 mg
目录价：	569.8
库存状态：	3周
CAS编号：	1272519-89-7
应用范围：
种属来源：
相关信息：
CAY10649 Exclusive Cayman Chemical Item Number 10804 Description 5-Lipoxygenase (5-LO) catalyzes the biosynthesis of leukotrienes, which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction.1↗ CAY10649 is a thiazolinone compound that demonstrates direct inhibition of 5-LO product formation in intact polymorphonuclear leukocytes (PMNL) (IC50 = 0.28 μM) and a soluble fraction of a S100 PMNL cell lysate (IC50 = 0.09 μM) after stimulation with calcium and arachidonic acid.2↗ Formal Name (Z)-2-(4-chlorophenyl)-5-(4-methoxybenzylidene)thiazol-4(5H)-one CAS Number 1272519-89-7 Molecular Formula C17H12ClNO2S Formula Weight 329.8 Formulation A crystalline solid Purity ≥98% λmax 297, 428 nm Stability 2 years Storage -20°C Shipping Room temperature in continental US; may vary elsewhere SMILES COC1=CC=C(/C=C2C(N=C(C3=CC=C(Cl)C=C3)S/2)=O)C=C1 InCHI Code 1S/C17H12ClNO2S/c1-21-14-8-2-11(3-9-14)10-15-16(20)19-17(22-15)12-4-6-13(18)7-5-12/h2-10H,1H3/b15-10- InCHI Key BYPSEBXZQCBFIP-GDNBJRDFSA-N
保存条件：	-20°C
说明书地址：	点击查看详细

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