CAY10650

产品编号：	10743-10 查看说明书
产品名称：	CAY10650 .0 订购此产品
供应商：	Cayman
规格：	10 mg
目录价：	6406.4
库存状态：	3周
CAS编号：	1233706-88-1
应用范围：
种属来源：
相关信息：
CAY10650 Exclusive Cayman Chemical Item Number 10743 Description Cytosolic phospholipase A2α (cPLA2α) specifically catalyzes the hydrolysis of arachidonic acid from the sn-2-ester position of membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes, both important mediators of the inflammatory process.1↗ CAY10650 is a highly potent (IC50 = 12 nM) cPLA2α inhibitor.2↗ It demonstrates strong anti-inflammatory effects when applied topically at a dose of 0.1 mg/ear in a mouse model of acute irritant contact dermatitis.2↗ The phase I metabolite of this compound, CAY10641 (Item No. 10662), is also available. Formal Name 3-(2-methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid CAS Number 1233706-88-1 Molecular Formula C28H25NO6 Formula Weight 471.5 Formulation A crystalline solid Purity ≥98% λmax 231, 300 nm Stability 2 years Storage -20°C Shipping Room temperature in continental US; may vary elsewhere SMILES O=C(CN1C(C=CC(C(O)=O)=C2)=C2C(C(C(C)C)=O)=C1)COC3=CC=C(OC4=CC=CC=C4)C=C3 InCHI Code 1S/C28H25NO6/c1-18(2)27(31)25-16-29(26-13-8-19(28(32)33)14-24(25)26)15-20(30)17-34-21-9-11-23(12-10-21)35-22-6-4-3-5-7-22/h3-14,16,18H,15,17H2,1-2H3,(H,32,33) InCHI Key HTOJZPHWNDZOPQ-UHFFFAOYSA-N
保存条件：	-20°C
说明书地址：	点击查看详细

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