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CB-13
Cayman Chemical Item Number 10010398
Description CB-13 is a dual agonist of the CB1 (IC50 = 15 nM) and CB2 (IC50 = 98 nM) receptors.1↗ In rats, oral CB-13 (3 mg/kg) potently blocks CB1-dependent neuropathic mechanical hyperalgesia, shows limited brain penetration, and exhibits good oral bioavailability.1↗ CB-13 does not possess genotoxic potential, as indicated by negative results in both chromosome aberration and reverse mutation assays.1↗ The effects of CB-13 on other aspects of CB signaling have not been assessed.
Synonyms CRA-13
Formal Name 1-naphthalenyl[4-(pentylox)-1-naphthalenyl]-methanone
CAS Number 432047-72-8
Molecular Formula C26H24O2
Formula Weight 368.5
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CCCCCOc1ccc(c2ccccc12)C(=O)c1cccc2ccccc12
InCHI Code 1S/C26H24O2/c1-2-3-8-18-28-25-17-16-24(21-13-6-7-14-22(21)25)26(27)23-15-9-11-19-10-4-5-12-20(19)23/h4-7,9-17H,2-3,8,18H2,1H3
InCHI Key RSUMDJRTAFBISX-UHFFFAOYSA-N |