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CD25 Monoclonal PE Antibody (Clone 143-13)

产品编号: 10339-1     查看说明书
产品名称: CD25 Monoclonal PE Antibody (Clone 143-13)  .0   订购此产品 
供应商: Cayman
规格: 1 ea
目录价: 4046
库存状态: 3周
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CD25 Monoclonal PE Antibody (Clone 143-13) Exclusive Cayman Chemical Item Number 10339 Description Clone designation: 143-13 · Host: mouse · Application(s): (+) FC, ICC, and IHC (frozen sections); (−) WB · Interleukin-2 (IL-2) elicits its effects by binding to a multi-subunit cell-surface receptor that is inducible by various mitogens.1↗,2↗,3↗ The highest affinity for IL-2 is achieved when all 3 subunits (IL-2Rα or CD25, IL-2Rβ or CD122, and IL-2Rγ or CD132) are expressed together forming a heterotrimeric complex4↗. CD25 is inducible in T-cells by antigen, mitogen or antibodies bound to the T-cell receptor CD3.2↗,5↗ Binding of IL-2 to IL-2R on NK cells results in their conversion to LAK cells, which release several other cytokines (TNF, INF-γ, and GM-CSF).4↗,6↗ Activated T-cells will respond to IL-2 by proliferating and secreting cytokines and cytolytic molecules. Activated B cells will proliferate and secrete antibodies.7↗ Synonyms Interleukin-2 receptor α subunit,Tac,IL-2Rα,p55 Formulation 100 µg of purified IgG1-PE conjugate in 500 µl TBS, pH 7.4, containing 50% glycerol, 5 mg/ml BSA, and 0.02% sodium azide Stability 1 year Storage 4°C Shipping Wet ice in continental US; may vary elsewhere Specificity Human CD25
保存条件: 4°C
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