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分子生化试剂 >> 生化试剂 |
CD25 Monoclonal PE Antibody (Clone 143-13)
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产品编号: |
10339-1
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产品名称:
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CD25 Monoclonal PE Antibody (Clone 143-13) .0 订购此产品 |
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供应商:
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Cayman |
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规格: |
1 ea |
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目录价: |
4046 |
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库存状态: |
3周 |
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CAS编号:
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应用范围: |
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种属来源: |
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相关信息: |
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CD25 Monoclonal PE Antibody (Clone 143-13) Exclusive
Cayman Chemical Item Number 10339
Description
Clone designation: 143-13 · Host: mouse · Application(s): (+) FC, ICC, and IHC (frozen sections); (−) WB · Interleukin-2 (IL-2) elicits its effects by binding to a multi-subunit cell-surface receptor that is inducible by various mitogens.1↗,2↗,3↗ The highest affinity for IL-2 is achieved when all 3 subunits (IL-2Rα or CD25, IL-2Rβ or CD122, and IL-2Rγ or CD132) are expressed together forming a heterotrimeric complex4↗. CD25 is inducible in T-cells by antigen, mitogen or antibodies bound to the T-cell receptor CD3.2↗,5↗ Binding of IL-2 to IL-2R on NK cells results in their conversion to LAK cells, which release several other cytokines (TNF, INF-γ, and GM-CSF).4↗,6↗ Activated T-cells will respond to IL-2 by proliferating and secreting cytokines and cytolytic molecules. Activated B cells will proliferate and secrete antibodies.7↗
Synonyms Interleukin-2 receptor α subunit,Tac,IL-2Rα,p55
Formulation 100 µg of purified IgG1-PE conjugate in 500 µl TBS, pH 7.4, containing 50% glycerol, 5 mg/ml BSA, and 0.02% sodium azide
Stability 1 year
Storage 4°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity Human CD25
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保存条件: |
4°C |
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说明书地址: |
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