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Chemokine-Like Receptor 1 Blocking Peptide

产品编号: 10326-200     查看说明书
产品名称: Chemokine-Like Receptor 1 Blocking Peptide  .0   订购此产品 
供应商: Cayman
规格: 200 碌g
目录价: 1498
库存状态: 3周
CAS编号:
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Chemokine-Like Receptor 1 Blocking Peptide Cayman Chemical Item Number 10326 Description Chemokine-Like Receptor 1 (CMKLR1) is a G protein-coupled receptor relevant to the cellular chemotaxis of dendritic cells and macrophages.1↗ This receptor is also expressed in brain, liver, lung, and kidney tissues.1↗,2↗ Chemerin (TIG2) has been identified as the natural ligand for this receptor.3↗ Resolvin E1 has also been identified as a ligand for CMKLR1; acting to dampen cellular responses to inflammation.1↗,4↗,5↗ Chemerin is an 18 kDa protein that plays a role in immunity, inflammation, chemotaxis, and has been identified as an adipokine.2↗,6↗,7↗ Human CMKLR1 shares 80% sequence homology with its murine ortholog.3↗ The human receptor exists in two isoforms, differing only by two amino acids due to a premature stop codon. Isoform one has 363 amino acids and an expected molecular weight of 42.3 kDa. Cayman’s CMKLR1 polyclonal antibody recognizes the C-terminal region of the protein and cell permeabilization is recommended prior to whole cell staining. Synonyms CMKLR1,DEZ,Resolvin E1 Receptor,GPCR ChemR23 Formulation 200 µg of peptide in 200 μl TBS, pH 7.4, containing 0.1% BSA, and 0.02% sodium azide Stability 2 years Storage -20°C Shipping Wet ice in continental US; may vary elsewhere
保存条件: -20°C
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