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分子生化试剂 >> 生化试剂 |
Chemokine-Like Receptor 1 Blocking Peptide
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产品编号: |
10326-200
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产品名称:
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Chemokine-Like Receptor 1 Blocking Peptide .0 订购此产品 |
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供应商:
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Cayman |
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规格: |
200 碌g |
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目录价: |
1498 |
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库存状态: |
3周 |
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CAS编号:
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应用范围: |
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相关信息: |
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Chemokine-Like Receptor 1 Blocking Peptide
Cayman Chemical Item Number 10326
Description
Chemokine-Like Receptor 1 (CMKLR1) is a G protein-coupled receptor relevant to the cellular chemotaxis of dendritic cells and macrophages.1↗ This receptor is also expressed in brain, liver, lung, and kidney tissues.1↗,2↗ Chemerin (TIG2) has been identified as the natural ligand for this receptor.3↗ Resolvin E1 has also been identified as a ligand for CMKLR1; acting to dampen cellular responses to inflammation.1↗,4↗,5↗ Chemerin is an 18 kDa protein that plays a role in immunity, inflammation, chemotaxis, and has been identified as an adipokine.2↗,6↗,7↗ Human CMKLR1 shares 80% sequence homology with its murine ortholog.3↗ The human receptor exists in two isoforms, differing only by two amino acids due to a premature stop codon. Isoform one has 363 amino acids and an expected molecular weight of 42.3 kDa. Cayman’s CMKLR1 polyclonal antibody recognizes the C-terminal region of the protein and cell permeabilization is recommended prior to whole cell staining.
Synonyms CMKLR1,DEZ,Resolvin E1 Receptor,GPCR ChemR23
Formulation 200 µg of peptide in 200 μl TBS, pH 7.4, containing 0.1% BSA, and 0.02% sodium azide
Stability 2 years
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
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保存条件: |
-20°C |
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说明书地址: |
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