|
COX-2 (mouse) Polyclonal FITC AntibodyExclusive
Cayman Chemical Item Number 10010096
Description Antigen:mouse COX-2 amino acids 570-598 (DPQPTKTATINASASHSRLDDINPTVLIK) · Host:rabbit · Application(s):FC, IF, and WB · The primary use of this antibody conjugate is for the detection of cyclooxygenase 2 (COX-2) in mouse samples by direct immunolabeling. COX catalyze the first step in the biosynthesis of prostaglandins (PGs), thromboxanes, and prostacyclins: the conversion of arachidonic acid to PGH2. Discoveries of the induction of COX by a variety of stimuli such as phorbol esters, lipopolysaccharides, and cytokines led to the hypothosis that the inducible form of COX, COX-2, is responsible for the biosynthesis of PGs under acute inflammatory conditions.1↗,2↗ COX-2 is a 72 kDa protein which has been cloned from a variety of species including human, mouse, rat, and sheep.3↗,4↗,5↗,6↗
Synonyms Cyclooxygenase 2 PGHS2 Prostaglandin H Synthase 2
Formula Weight 72.0
Formulation Peptide affinity-purified IgG-fluorescein conjugate in PBS, pH 7.2, containing 50% glycerol, 0.5 mg/ml BSA, and 0.02% sodium azide
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
Specificity Human COX-2 Mouse COX-2 Rat COX-2 |