Cystathionine 纬-Lyase (human recombinant)

产品编号：	10329-25 查看说明书
产品名称：	Cystathionine 纬-Lyase (human recombinant) .0 订购此产品
供应商：	Cayman
规格：	25 碌g
目录价：	1386
库存状态：	3周
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Cystathionine γ-Lyase (human recombinant) Cayman Chemical Item Number 10329 Description Source: active recombinant protein expressed in E. coli · Mr: 44.5 kDa · Transsulfuration and reverse transsulfuration comprise part of the metabolic interconversion of the sulfur-containing amino acids cysteine and methionine.1↗ Reverse transsulfuration is catalyzed by the enzymes cystathionine β-synthase (CBS) and cystathionine γ-lyase (CGL) in fungi and mammals.1↗ Specifically, CGL catalyzes the conversion of cystathionine to cysteine in a pyridoxal-5'-phosphate-dependant reaction.2↗ At elevated levels, homocysteine is an independent risk factor for cardiovascular diseases and other complex disorders.2↗ The mammalian transsulfuration pathway is one of two major metabolic routes for homocysteine removal. Besides homocysteine removal, transsulfuration contributes significantly to the intracellular cysteine pool.2↗ Cysteine is used for biosynthesis of glutathione, and is also the primary substrate for H2S biosynthesis. CGL is one of two major enzymes that catalyzes the formation of H2S from cysteine. 2↗ H2S generation is a biological gasotransmitter, a neuromodulator, a vasodilator, and plays an important role in inflammation.2↗ Synonyms CGL,Cystathionase,CTH Formulation 70 mM Tris, pH 8.1, containing 150 mM sodium chloride, 20% glycerol, and 10 µM pyridoxal-5’-phosphate Purity ≥85% Stability 6 months Storage -80°C Shipping Dry ice in continental US; may vary elsewhere
保存条件：	-80°C
说明书地址：	点击查看详细

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