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Daidzein
Cayman Chemical Item Number 10005166
Description
Daidzein is an isoflavonoid phytoestrogenic compound found in soybeans, pea pods, clover, kudzu, and other legumes. The estimated human normal dietary intake of daidzein, primarily as glycosides, is 0 to 0.3 mg/kg. Daidzein is present in much greater amounts in nutritional supplements. Daidzein is inactive as a tyrosine-specific inhibitor of protein kinase activity, and can be used as a negative control for genistein.1↗ In adult animals, dietary genistein has numerous effects based on estrogen agonist/antagonist and antioxidant activities.2↗
1 Akiyama, T., Ishida, J., Nakagawa, S., et al. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 262(1) 5592-5595 (1987).
2 Lamartiniere, C.A., Cotroneo, M.S., Fritz, W.A., et al. Genistein chemoprevention: Timing and mechanisms of action in murine mammary and prostate. J Nutr 132 552S-558S (2002).
Synonyms Isoflavone
Formal Name 7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CAS Number 486-66-8
Molecular Formula C15H10O4
Formula Weight 254.2
Formulation A crystalline solid
Purity ≥95%
λmax 249, 301 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES Oc1ccc(cc1)c1coc2cc(O)ccc2c1=O
InCHI Code 1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InCHI Key ZQSIJRDFPHDXIC-UHFFFAOYSA-N |