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D-erythro-MAPP

产品编号: 10165-500     查看说明书
产品名称: D-erythro-MAPP  .0   订购此产品 
供应商: Cayman
规格: 500 碌g
目录价: 107.8
库存状态: 3周
CAS编号: 143492-38-0
应用范围:
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D-erythro-MAPP Cayman Chemical Item Number 10165 Description:D-erythro-MAPP is an analog of ceramide that suppresses growth of HL-60 cancer cells in culture. D-erythro-MAPP inhibits alkaline ceramidase with an IC50 of approximately 5 µM.1↗ Treatment of cultured cells with D-erythro-MAPP elevates the levels of endogenous ceramide, resulting in growth suppression and G0/G1 cell cycle arrest. Synonyms (1S,2R-D-erythro-2-N-myristoylamino)-1-phenyl-1-propanol Formal Name N-​[(1S,​5S,​6R)-​5-​hydroxy-​5-​[(1E,​3E,​5E)-​7-​[(2-​hydroxy-​5-​oxo-​1-​cyclopenten-​1-​yl)amino]-​7-​oxo-​1,​3,​5-​heptatrien-​1-​yl]-​2-​oxo-​7-​oxabicyclo[4.1.0]hept-​3-​en-​3-​yl]-​2E,​4E,​6R-​trimethyl-​2,​4-​decadienamide CAS Number 143492-38-0 Molecular Formula C23H29NO2 Formula Weight 361.6 Formulation A crystalline solid Purity ≥98% Stability 1 year Storage -20°C Shipping Room temperature in continental US; may vary elsewhere SMILES O[C@H]​([C@H]​(N(C(CCCCCCCCCCCCC)​=O)​[H]​)​C)​C1=CC=CC=C1 InCHI Code ​1S/C23H39NO2/c1-3-4-5-6-7-8-9-10-11-12-16-19-22(25)​24-20(2)​23(26)​21-17-14-13-15-18-21/h13-15,17-18,20,23,26H,3-12,16,19H2,1-2H3,(H,24,25)​/t20-,23-/m1/s1 InCHI Key YLAZEWZHIRBZDA-NFBKMPQASA-N
保存条件: -20°C
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