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D-erythro-Sphinganine
Cayman Chemical Item Number 10007945
Description
D-erythro-Sphinganine is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins,1↗,2↗ as well as in some cancers.3↗ Sphinganine can block protein kinase C activation in some cases but not others.4↗,5↗ Sphinganine-1-phosphate can emulate sphingosine-1-phosphate in cell signaling or have opposite intracellular effects.6↗,7↗,8↗
Synonyms Dihydro-D-erythro Sphingosine
D-erythro-Dihydrosphingosine
Formal Name 2S-amino-1,3R-octadecanediol
CAS Number 764-22-7
Molecular Formula C18H39NO2
Formula Weight 301.5
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES OC[C@H](N)[C@H](O)CCCCCCCCCCCCCCC
InCHI Code 1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1
InCHI Key OTKJDMGTUTTYMP-ZWKOTPCHSA-N |