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Dihomo-γ-Linolenoyl Ethanolamide
Cayman Chemical Item Number 90235
Description
Dihomo-γ-linolenoyl ethanolamide is an endocannabinoid containing dihomo-γ-linoleate in place of the arachidonate moiety of AEA. Dihomo-γ-linolenoyl ethanolamide binds to recombinant human CB1 and CB2 receptors with Ki values of 857 and 598 nM, respectively.1↗ Its specific role and relative importance as a cannabinergic neurotransmitter has not been elucidated.2↗
1 Felder, C.C., Joyce, K.E., Briley, E.M., et al. Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. Mol Pharmacol 48 443-450 (1995).
2 Hanus, L., Gopher, A., Almog, S., et al. Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. J Med Chem 36 3032-3034 (1993).
Formal Name N-(2-hydroxyethyl)-8Z,11Z,14Z-eicosatrienamide
CAS Number 150314-34-4
Molecular Formula C22H39NO2
Formula Weight 349.6
Formulation A solution in ethanol
Purity >98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)NCCO
InCHI Code 1S/C22H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,24H,2-5,8,11,14-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-
InCHI Key ULQWKETUACYZLI-QNEBEIHSSA-N |