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HKCA
Heat-killed preparation of Candida albicans
HKCA activates the β-glucan specific dectin-1 receptor, which is expressed on phagocytes. β-Glucans are glucose polymers found in the cell walls of fungi, such as zymosan (a cell wall preparation of Saccharomyces cerevisiae) and Candida albicans. Dectin-1 binds and internalizes β-glucans and mediates the activation of NF-κB and subsequent secretion of proinflammatory cytokines.
Specificity: Dectin-1 agonist
Working concentration: 108 cells/ml
Endotoxin level: EndoFit™ (<0.001 EU/μg) |