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分子生化试剂 >> 生化试剂 |
17-AAG
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产品编号： |
ant-agl-25
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产品名称：
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17-AAG .0 订购此产品 |
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供应商：
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Invivogen |
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规格： |
25 mg |
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目录价： |
5628 |
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库存状态： |
二周到货 |
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CAS编号：
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应用范围： |
生化试验 |
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种属来源： |
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相关信息： |
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17-AAG
17-Allylamino-17-demethoxygeldanamycin- An Hsp90 inhibitor
17-Allylamino-17-demethoxygeldanamycin (17AAG) is a less toxic and more stable analog of geldanamycin (GA) [1]. Even though 17-AAG binding to Hsp90 is weaker than GA,17-AAG displays similar antitumor effects as GA and a better toxicity profile. 17-AAG is currently in phase I clinical trial in several centers worldwide. Preliminary data obtained from these trials demonstrate that antitumor activity is achieved at concentrations below the maximum tolerated dose [2].
Working concentration: 10 nM - 10 μM
CAS number: 75747-14-7
Formula: C31H43N3O8
Molecular weight: 586
Solubility: Soluble in DMSO (10 mg/ml)
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