利福平 Rifampicin
中文名:利福平,甲哌利福霉素,力复平、利米定
英文名:Rifampicin ,RFP, 3-[[(4-甲基-1-哌嗪基)亚氨基]甲基]-利福霉素
CAS No. 13292-46-1
用途: 对结核杆菌和其他分支杆菌(包括麻风杆菌等),在宿主细胞内、外均有明显的杀菌作用。对脑膜炎球菌、流感嗜血杆菌、金黄色葡萄球菌、表皮链球菌、肺炎军团菌等也有一定的抗菌作用。对某些病毒、衣原体也有效。
Sigma相关产品资料:
Sigma R3501 Rifampicin
≥97% (HPLC), powder
Synonym: 3-(4-Methylpiperazinyliminomethyl)rifamycin SV, Rifampin, Rifamycin AMP
CAS Number: 13292-46-1
Linear Formula: C43H58N4O12
Molecular Weight: 822.94
Beilstein Registry Number: 5723476
EC Number: 236-312-0
MDL number: MFCD00151389
PubChem Substance ID: 24899363
Description
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Biochem/physiol Actions Inhibits the assembly of DNA and protein into mature virus particles.
Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase.
性质
assay ≥97% (HPLC)
form powder
color orange-brown to red-brown
solubility H2O: 1.3 mg/mL (pH 4.3)
DMSO: 100 mg/mL
H2O: 2.5 mg/mL at 25 °C (pH 7.3)
storage temp. −20°C
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