中文名:妥布霉素,妥布拉霉素,乃柏欣、托普霉素、妥布接霉素英文名:Tobramycin , Gernebcin ,Tobracin , NF 6,Obracin性状:白色结晶性粉末。碱性。有吸湿性。易溶于水。比旋光度 [α]D+128°。半数致死量(大鼠,皮下)969mg/kg。用途:妥布霉素能够联结在30S和50S的联结位置,阻碍70S复合物的形成,使mRNA不能翻译成蛋白质,导致细胞死亡。主要对革兰阴性菌,如绿脓杆菌、大肠杆菌、克雷白杆菌、肠杆菌属、变形杆菌、枸橼酸杆菌有效。Sigma相关产品资料:Sigma T4014 TobramycinSynonym: O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1→4)]-2-deoxy-D-streptamineCAS Number: 32986-56-4Linear Formula: C18H37N5O9Molecular Weight: 467.51Beilstein Registry Number: 1357507EC Number: 251-322-5MDL number: MFCD00077885PubChem Substance ID: 24900188 DescriptionBiochem/physiol Actions Tobramycin is an aminoglycoside. Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Spectrum of Activity: Gram negative bacteria. Not effective against Enterococci. 性质storage temp. 2-8°C