产品说明 A potent, cell-permeable, reversible γ-secretase inhibitor that preferentially appears to inhibit the secretion of Aβ1-40 (>90%) over Aβ1-42 (~15%). Aβtotal IC50 ~ 15 µM; Aβ1-40 IC50 ~ 22 µM; Aβ1-42 IC50 > 50 µM in CHO cells stable transfected with the cDNA encoding βAPP695. Reported to be about 10-fold more potent than Z-Val-Phe-CHO (MDL 28170; Cat. No. 208722). 产品信息 Form White lyophilized solid Primary Target secretion of Aβ1-40 Primary Target IC50 22 µM Secondary target Aβtotal IC50 ~ 15 µM;; Aβ1-42 IC50 > 50 µM in CHO cells stable transfected with the cDNA encoding βAPP695 Protect from Light 是的 Packaged under inert gas 是的 Cell permeable 是的 Reversible 是的 Purity ≥95% by HPLC Chemical formula C23H34N2O5 Storage -20°C Ship Ambient Temperature Only Standard Handling