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α-Amyloid Precursor Protein Modulator
(2S,5S)-(E,E)-8-(5-(4-(Trifluoromethyl)phenyl)-2,4-pentadienoylamino)benzolactam, PKC Activator V
A cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblast AG06848. Displays a marked loss of tumor promoting activity.
产品信息
Form Orange solid
Molar mass 501.5
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥95% by HPLC
Solubility DMSO or MeOH
Chemical formula C27H30F3N3O3
CAS number 497259-23-1
商店和运输信息
Storage -20°C
Ship Blue Ice Only
Standard Handling |