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PKCβ Inhibitor
3-(1-(3-Imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anilino-1H-pyrrole-2,5-dione
An anilino-monoindolylmaleimide compound that acts as a potent, cell-permeable, reversible, and ATP-competitive inhibitor of PKCβ isozymes (IC50 = 5 nM and 21 nM for human PKCβII and βI) and displays greater selectivity over PKCα, γ,& ε (IC50 = 331 nM, > 1 µM, and 2.8 µM, respectively).
产品信息
Form Orange solid
Primary Target PKCβII, βI
Primary Target IC50 5 nM, 21 nM
Secondary target PKCα, γ, ε (IC50 = 331 nM, > 1 µM, 2.8 µM, respectively)
Molar mass 411.5
Protect from Light 是的
Packaged under inert gas 是的
ATP Competitive 是的
Purity ≥90% by HPLC
Solubility DMSO
Chemical formula C24H21N5O2
CAS number 257879-35-9
商店和运输信息
Storage +2°C to +8°C
Ship Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Standard Handling |