(±)-Propranolol, Hydrochloride (±)-1-(Isopropylamino)-3-(1-naphthyloxy)-2-propanol, HCl A highly lipophilic agent that blocks both β1 and β2 adrenergic receptors with equal potency. Has no effect on α-adrenergic receptors. Also binds to 5HT-1B receptors with high affinity (Ki = 17 nM) in contrast to 5HT-1D receptors (Ki = 10.2 µM). Readily enters the central nervous system. Blocks phospholipase D-derived diacylglycerol (DAG) formation by inhibiting phosphatidate phosphohydrolase. Useful tool for discriminating between phospholipase D- or phospholipase C-mediated DAG production. An anti-hypertensive agent that is also used in the treatment of cardiac arrhythmias. 产品信息 Form White solid Molar mass 295.8 Purity ≥98% by titration Solubility MeOH or H2O Chemical formula C16H21NO2 · HCl RTECS UB7526000 CAS number 3506-09-0 Merck USA index 14, 7840 商店和运输信息 Storage -20°C Ship Ambient Temperature Only Harmful