Myosin Light Chain Kinase Inhibitor Peptide 18 MLCK Inhibitor Peptide 18, H-RKKYKYRRK-NH2, MLCK Inhibitor IV A highly basic, cell-permeable, nonapeptide that acts as a selective Myosin Light Chain Kinase (MLCK) inhibitor (IC50 = 50 nM). The inhibition is competitive with respect to the peptide substrate (Ki = 52 nM) and displays a mixed mode of inhibition with respect to ATP. Does not interfere with kinase activation by calmodulin (CaM), nor does it inhibit the activities of CaMKII and PKA. 产品信息 Peptide Sequence H-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2 Form White lyophilized solid Formulation Supplied as a trifluoroacetate salt. Primary Target Mlck Primary Target IC50 50 nM Secondary target peptide substrate (IC50 = 52 nM) Molar mass 1324.6 Hygrocopic 是的 Packaged under inert gas 是的 Purity ≥97% by HPLC Solubility DMSO or H2O Chemical formula C60H105N23O11 商店和运输信息 Storage -20°C Ship Blue Ice Only Standard Handling