D-erythro-MAPP (1S,2R)-D-erythro-2-(N-Myristoylamino)-1-phenyl-1-propanol A synthetic analog of ceramide. Shown to selectively inhibit alkaline ceramidase both in vitro and in HL-60 cells (IC50 = 1-5 µM for alkaline ceramidase versus IC50 > 500 µM for acid ceramidase). This inhibition results in over 3-fold increase in endogenous ceramide in treated cells due to lack of breakdown of ceramide to sphingosine. 产品信息 Form Solid Molar mass 361.6 Purity ≥98% by NMR Solubility EtOH Chemical formula C23H39NO2 CAS number 143492-38-0 商店和运输信息 Storage -20°C Ship Ambient Temperature Only Standard Handling