MMP-2/MMP-9 INHIBITOR IV

MMP-2/MMP-9 Inhibitor IV
A potent, selective, slow-binding and mechanism-based inhibitor of human gelatinases, MMP-2 (Ki = 13.9 nM), and MMP-9 (Ki = 600 nM). This inhibitor appears to behave similarly to TIMP-1 and TIMP-2 in the slow-binding component of inhibition. Also exhibits a covalent mechanism-based behavior in inhibition of these enzymes. Binds directly to the catalytic zinc ion on MMP-2.
产品信息
Form  Off-white solid
Primary Target  MMP-2
Primary Target Ki  13.9 nM
Secondary target  MMP-9 (Ki = 600 nM)
Molar mass  306.4
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥ 95% by HPLC
Solubility  DMSO
Chemical formula  C15H14O3S2
CAS number  292605-14-2
Declaration  Sold under license of U.S. Patent 6,703,415.
商店和运输信息
Storage  -20°C
Ship  Ambient Temperature Only
Standard Handling