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Gö 7874, Hydrochloride
A cell-permeable, potent, reversible, ATP-competitive, and selective inhibitor of protein kinase C (IC50 = 4 nM for rat brain PKC). Inhibits protein kinase A (IC50 = 510 nM), protein kinase G (IC50 = 4.8 µM), and myosin light chain kinase (IC50 = 120 nM) at much higher concentrations.
产品信息
Form Amber solid
Primary Target PKC
Primary Target IC50 4 nM
Secondary target MLCK (IC50 = 120 nM), PKA (IC50 = 150 nM)
Molar mass 507.0
Protect from Light 是的
Purity ≥97% by HPLC
Solubility DMSO
Chemical formula C27H26N4O4 · HCl
CAS number 287935-76-6
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling |