Glyburide A sulfonylurea that selectively blocks ATP-sensitive K+ channels. Reduced K+ conductance causes membrane depolarization and influx of Ca2+ through voltage sensitive Ca2+ channels. Blocks vascular smooth muscle relaxation produced by KATP channel openers. Inhibits the vasorelaxing effects of nitric oxide. 产品信息 Form White solid Molar mass 494.0 Purity ≥98% by TLC Solubility DMSO or EtOH (slightly) Chemical formula C23H28ClN3O5S RTECS YS4725200 CAS number 10238-21-8 Merck USA index 14, 4478 商店和运输信息 Storage +15°C to +30°C Ship Ambient Temperature Only Standard Handling