Glucagon-Like Peptide 1 Receptor Agonist A nonpeptidic quinoxaline compound that acts as a GLP-1R agonist and an allosteric modulator of GLP-1 binding. Shown to induce GLP-1R-mediated cAMP production in BHK plasma membrane preparations (EC50 = 101 nM) and potentiate glucose-dependent insulin release in pancreatic islets derived from wild-type, but not GLP-1R -/-, mice. Unlike GLP-1, its biological activity is not inhibited by orthosteric antagonists such as Exendin. 产品信息 Form Yellow solid Molar mass 348.3 Protect from Light 是的 Packaged under inert gas 是的 Purity ≥97% by HPLC Solubility DMSO or EtOH Chemical formula C13H15Cl2N3O2S CAS number 281209-71-0 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Regulatory Review