FPTASE, RAT, RECOMB., E. COLI

FPTase, Rat, Recombinant, E. coli
Recombinant, rat FPTase expressed in E. coli. A heterodimeric enzyme that catalyzes the transfer of a 15-carbon isoprenoid group to a variety of cellular proteins including Ras. Recognizes the C-terminal CAAX cysteine motif where the farnesylated cysteine is followed by two aliphatic amino acids and either leucine or serine. M.W. α-subunit: ~48,000; β-subunit: ~46,000
产品信息
Form  Liquid
Formulation  In 40 mM NaCl, 25 mM HEPES, 5 mM DTT, pH 7.2.
Avoid freeze/thaw  是的
Biological activity  1 pmol of FPTase will transfer 1 pmol of farnesyl to H-Ras in 15 min at 37°C.
Purity  ≥85% by SDS-PAGE
商店和运输信息
Storage  ≤ -70°C
Ship  Dry Ice Only
Standard Handling