cFMS Receptor Tyrosine Kinase Inhibitor A cell-permeable diaminopyrimidine compound that acts as a potent, selective, and ATP-competitive inhibitor of cFMS kinase activity (IC50 = 30 nM) with minimal inhibition towards a panel of 26 other kinases (IC50 >5 µM). Shown to selectively inhibit cFMS-mediated cellular functions in vitro as well as CSF-1-dependent tumor growth in vivo. A 10 mM (1 mg/273 µl) solution of cFMS Receptor Tyrosine Kinase Inhibitor (Cat. No. 344041) in DMSO is also available. 产品信息 Form Off-white solid Primary Target CFMS Primary Target IC50 30 nM Molar mass 366.4 Protect from Light 是的 Packaged under inert gas 是的 Cell permeable 是的 ATP Competitive 是的 Purity ≥97% by HPLC Solubility DMSO Chemical formula C20H22N4O3 CAS number 870483-87-7 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Standard Handling