CYCLOPHILIN A, HU., RECOM

Cyclophilin A, Human, Recombinant, E. coli
Recombiant, human cyclophilin A expressed in E. coli. An ubiquitous enzyme that catalyzes the cis-trans-isomerization of X-Pro peptide bonds. Binds to proteins and acts as a chaperone in protein folding. Incorporates into HIV-1 virons and is believed to be essential for viral infectivity. Cyclophilin binds to the immunosuppressant Cyclosporin A (Cat. No. 239835). This complex then binds calcineurin (PP2B) and inhibits its phosphatase activity.
产品信息
Form  Liquid
Formulation  In 20 mM Tris-HCl, pH 7.8.
Molar mass  18000
Purity  ≥90% by SDS-PAGE
EC number  5.2.1.8
CAS number  95076-93-0
商店和运输信息
Storage  +2°C to +8°C
Ship  Blue Ice Only
Standard Handling
安全标示
S Phrase  S: 24/25-36
Avoid contact with skin and eyes.
Wear suitable protective clothing.