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Cycloheximide
An antifungal antibiotic that inhibits protein synthesis in eukaryotes but not prokaryotes. Competitively inhibits hFKBP12 (Ki = 3.4 µM). Triggers apoptosis in HL-60 cells, T cell hybridomas, Burkitt’s lymphoma cells, and other cell types. A 100 mg/ml solution of Cycloheximide (Cat. No. 239765) in DMSO (sterile-filtered) is also available.
产品信息
Form Off-white solid
Primary Target hFKBP12
Primary Target Ki 3.4 µM
Molar mass 281.3
Purity ≥90% by assay
Solubility EtOH or MeOH
Chemical formula C15H23NO4
RTECS MA4375000
CAS number 66-81-9
Merck USA index 14, 2728
商店和运输信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +15°C to +30°C
Ship Ambient Temperature Only
Highly Toxic & Carcinogenic / Teratogenic
安全标示
S Phrase S: 45-53-61
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Avoid exposure - obtain special instructions before use.
Avoid release to the environment. Refer to special instructions/safety data sheet.
R Phrase R: 28-40-51/53-61
Very toxic if swallowed.
Limited evidence of a carcinogenic effect.
Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
May cause harm to the unborn child. |