Cathepsin D/E Substrate, Fluorogenic An internally quenched fluorogenic 11-mer peptide that acts as a sensitive and selective substrate for cathepsins D and E (kcat/Km = 15.6 µM-1s-1 and 10.9 µM-1s-1 for rat gastric cathepsin D and human erythrocyte cathepsin E, respectively), but not cathepsins B, H, or L . Cleavage occurs between Phe-Phe residues and results in enhanced fluorescence. A useful tool for inhibitors screening or for the determination of cathepsins D and E activities in crude extracts of various tissues and cell lysates. 产品信息 Peptide Sequence MOCAc-Gly-Lys-Pro-Ile-Leu-Phe~Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2 MOCAc = (7-Methoxycoumarin-4-yl)acetyl Form Yellow lyophilized solid Formulation Supplied as a trifluoroacetate salt. Molar mass 1756 Protect from Light 是的 Hygrocopic 是的 Packaged under inert gas 是的 Purity ≥97% by HPLC Excitation max. ~328 nm Emission max. ~393 nm Solubility DMSO Chemical formula C85H122N22O19 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Standard Handling