CASEIN KINASE II INHIBITOR III, TBCA

Casein Kinase II Inhibitor III, TBCA
(E)-3-(2,3,4,5-Tetrabromophenyl)acrylic acid, CKII Inhibitor, TBCA
A cell-permeable tetrabrominated cinnamic acid compound that acts as a potent and ATP-competitive inhibitor of Casein Kinase II (IC50 = 110 nM, Ki = 77 nM) with greater selectivity than TBB (Cat. Nos. 218697 and 218708) and DMAT (Cat. Nos. 218699 and 218706) against a panel of 28 commonly studied kinases. Shown to efficiently induces apoptosis in Jurkat cells (DC50 = 7.7 µM). Also available as a 25 mM solution in DMSO (Cat. No. 218861).
产品信息
Form  Off-white solid
Molar mass  463.8
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥95% by HPLC
Solubility  DMSO or EtOH
Chemical formula  C9H4Br4O2
CAS number  934358-00-6
商店和运输信息
Storage  +2°C to +8°C
Ship  Ambient Temperature Only
Irritant