产品信息: Form Off-white crystalline solid Primary Target calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase Hygrocopic 是的 Purity ≥99% by titration Contaminants Heavy metals: ≤0.002%; iron: ≤0.001%; sulfate: ≤0.05% Chemical formula C17H19ClN2S · HCl RTECS SO1750000 CAS number 69-09-0 Merck USA index 14, 2185 Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. Storage +15°C to +30°C Ship Ambient Temperature Only Toxic 产品说明: Inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase (IC50 = 17 µM). Acts as a peripheral vasodilator. Acts as an inhibitor of lysosomal sphingomyelinase and of TNF-α production. Inhibits nitric oxide synthase (NOS) in mouse brain and prevents lipopolysaccharide induction of NOS in murine lung. Shown to potently and specifically inhibit KSP/Eg5 (IC50 < 10 µM), and PLA2.