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Calmodulin Kinase IINtide
A potent and specific inhibitor of CaMK II (IC50 = 50 nM for both the total and Ca2+-independent CaMK II activity). Exhibits inhibitory activity across converged species, including rat brain, goldfish brain, and Drosophila (IC50 range 100-400 nM). Does not affect the activities of CaMK I, CaMK IV, CaMKK, PKA, or PKC. The peptide sequence corresponds to the inhibitory domain of CaMK IIN.
产品信息
Peptide Sequence H-Lys-Arg-Pro-Pro-Lys-Leu-Gly-Gln-Ile-Gly-Arg-Ala-Lys-Arg-Val-Val-Ile-Glu-Asp-Asp-Arg-Ile-Asp-Asp-Val-Leu-Lys-OH
Form Off-white solid
Formulation Supplied as a trifluoroacetate salt.
Primary Target cam Kinase-2
Primary Target IC50 50 nM
Secondary target rat brain, goldfish brain, and Drosophila (IC50 range 100-400 nM)
Molar mass 3115.7
Hygrocopic 是的
Packaged under inert gas 是的
Purity ≥95% by HPLC
Solubility DMSO
Chemical formula C136H240N44O39
商店和运输信息
Storage -20°C
Ship Ambient Temperature Only
Standard Handling |