Ca2+/Calmodulin Kinase II Inhibitor 281-309 A synthetic peptide that contains the CaM-binding, inhibitory, and autophosphorylation domains of CaM kinase II. Can be phosphorylated at Thr286 by PKC. Useful as a calmodulin binding peptide. Inhibits CaM kinase II (IC50 = 80 nM) by blocking Ca2+/calmodulin activation and enzyme active site (IC50 = 2 µM). 产品信息 Peptide Sequence H-Met-His-Arg-Gln-Glu-Thr-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH Form Lyophilized solid Formulation Supplied as a trifluoroacetate salt. Primary Target cam Kinase-2 Primary Target IC50 80nM Secondary target Ca2+/calmodulin (IC50 = 2 µM) Molar mass 3374.1 Hygrocopic 是的 Purity ≥97% by HPLC Sold on the basis of peptide content 是的 Solubility H2O Chemical formula C146H254N46O39S3 商店和运输信息 Storage -20°C Ship Ambient Temperature Only Standard Handling